gluc on human ldlr promoter reporter Search Results


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A, There is a reduction in liver uptake of radioactivity with increasing antibody mass (error bars show one standard deviation). B, Maximum-intensity projection image demonstrates the effect in a patient injected with 3 mg antibody (left) and a (different) patient injected with 47 mg <t>HuMab</t> <t>5B1</t> antibody 2 h before injection of 3 mg radiolabeled HuMab 5B (right). C, Fused PET/CT, PET, and contrast-enhanced CT of PDAC liver metastases in a patient who received 47 mg of HuMab 5B1 before injection of the radiolabeled antibody. Small liver metastases measuring less than 5 mm (red arrows) are visualized with high contrast. SUVs values were 101.4, 70.7, and 53.4 g/ml, respectively. Arrowhead indicates splenic infarct.
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A, There is a reduction in liver uptake of radioactivity with increasing antibody mass (error bars show one standard deviation). B, Maximum-intensity projection image demonstrates the effect in a patient injected with 3 mg antibody (left) and a (different) patient injected with 47 mg <t>HuMab</t> <t>5B1</t> antibody 2 h before injection of 3 mg radiolabeled HuMab 5B (right). C, Fused PET/CT, PET, and contrast-enhanced CT of PDAC liver metastases in a patient who received 47 mg of HuMab 5B1 before injection of the radiolabeled antibody. Small liver metastases measuring less than 5 mm (red arrows) are visualized with high contrast. SUVs values were 101.4, 70.7, and 53.4 g/ml, respectively. Arrowhead indicates splenic infarct.
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A, There is a reduction in liver uptake of radioactivity with increasing antibody mass (error bars show one standard deviation). B, Maximum-intensity projection image demonstrates the effect in a patient injected with 3 mg antibody (left) and a (different) patient injected with 47 mg <t>HuMab</t> <t>5B1</t> antibody 2 h before injection of 3 mg radiolabeled HuMab 5B (right). C, Fused PET/CT, PET, and contrast-enhanced CT of PDAC liver metastases in a patient who received 47 mg of HuMab 5B1 before injection of the radiolabeled antibody. Small liver metastases measuring less than 5 mm (red arrows) are visualized with high contrast. SUVs values were 101.4, 70.7, and 53.4 g/ml, respectively. Arrowhead indicates splenic infarct.
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A, There is a reduction in liver uptake of radioactivity with increasing antibody mass (error bars show one standard deviation). B, Maximum-intensity projection image demonstrates the effect in a patient injected with 3 mg antibody (left) and a (different) patient injected with 47 mg <t>HuMab</t> <t>5B1</t> antibody 2 h before injection of 3 mg radiolabeled HuMab 5B (right). C, Fused PET/CT, PET, and contrast-enhanced CT of PDAC liver metastases in a patient who received 47 mg of HuMab 5B1 before injection of the radiolabeled antibody. Small liver metastases measuring less than 5 mm (red arrows) are visualized with high contrast. SUVs values were 101.4, 70.7, and 53.4 g/ml, respectively. Arrowhead indicates splenic infarct.
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A, There is a reduction in liver uptake of radioactivity with increasing antibody mass (error bars show one standard deviation). B, Maximum-intensity projection image demonstrates the effect in a patient injected with 3 mg antibody (left) and a (different) patient injected with 47 mg <t>HuMab</t> <t>5B1</t> antibody 2 h before injection of 3 mg radiolabeled HuMab 5B (right). C, Fused PET/CT, PET, and contrast-enhanced CT of PDAC liver metastases in a patient who received 47 mg of HuMab 5B1 before injection of the radiolabeled antibody. Small liver metastases measuring less than 5 mm (red arrows) are visualized with high contrast. SUVs values were 101.4, 70.7, and 53.4 g/ml, respectively. Arrowhead indicates splenic infarct.
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A, There is a reduction in liver uptake of radioactivity with increasing antibody mass (error bars show one standard deviation). B, Maximum-intensity projection image demonstrates the effect in a patient injected with 3 mg antibody (left) and a (different) patient injected with 47 mg <t>HuMab</t> <t>5B1</t> antibody 2 h before injection of 3 mg radiolabeled HuMab 5B (right). C, Fused PET/CT, PET, and contrast-enhanced CT of PDAC liver metastases in a patient who received 47 mg of HuMab 5B1 before injection of the radiolabeled antibody. Small liver metastases measuring less than 5 mm (red arrows) are visualized with high contrast. SUVs values were 101.4, 70.7, and 53.4 g/ml, respectively. Arrowhead indicates splenic infarct.
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Marburg GmbH anatomia capitis humani
A, There is a reduction in liver uptake of radioactivity with increasing antibody mass (error bars show one standard deviation). B, Maximum-intensity projection image demonstrates the effect in a patient injected with 3 mg antibody (left) and a (different) patient injected with 47 mg <t>HuMab</t> <t>5B1</t> antibody 2 h before injection of 3 mg radiolabeled HuMab 5B (right). C, Fused PET/CT, PET, and contrast-enhanced CT of PDAC liver metastases in a patient who received 47 mg of HuMab 5B1 before injection of the radiolabeled antibody. Small liver metastases measuring less than 5 mm (red arrows) are visualized with high contrast. SUVs values were 101.4, 70.7, and 53.4 g/ml, respectively. Arrowhead indicates splenic infarct.
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Millipore human nucleus antibody h.huma
A, There is a reduction in liver uptake of radioactivity with increasing antibody mass (error bars show one standard deviation). B, Maximum-intensity projection image demonstrates the effect in a patient injected with 3 mg antibody (left) and a (different) patient injected with 47 mg <t>HuMab</t> <t>5B1</t> antibody 2 h before injection of 3 mg radiolabeled HuMab 5B (right). C, Fused PET/CT, PET, and contrast-enhanced CT of PDAC liver metastases in a patient who received 47 mg of HuMab 5B1 before injection of the radiolabeled antibody. Small liver metastases measuring less than 5 mm (red arrows) are visualized with high contrast. SUVs values were 101.4, 70.7, and 53.4 g/ml, respectively. Arrowhead indicates splenic infarct.
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Image Search Results


A, There is a reduction in liver uptake of radioactivity with increasing antibody mass (error bars show one standard deviation). B, Maximum-intensity projection image demonstrates the effect in a patient injected with 3 mg antibody (left) and a (different) patient injected with 47 mg HuMab 5B1 antibody 2 h before injection of 3 mg radiolabeled HuMab 5B (right). C, Fused PET/CT, PET, and contrast-enhanced CT of PDAC liver metastases in a patient who received 47 mg of HuMab 5B1 before injection of the radiolabeled antibody. Small liver metastases measuring less than 5 mm (red arrows) are visualized with high contrast. SUVs values were 101.4, 70.7, and 53.4 g/ml, respectively. Arrowhead indicates splenic infarct.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

Article Title: Retooling a Blood-based Biomarker: Phase I Assessment of the High-Affinity CA19-9 Antibody HuMab-5B1 for Immuno-PET Imaging of Pancreatic Cancer

doi: 10.1158/1078-0432.CCR-18-3667

Figure Lengend Snippet: A, There is a reduction in liver uptake of radioactivity with increasing antibody mass (error bars show one standard deviation). B, Maximum-intensity projection image demonstrates the effect in a patient injected with 3 mg antibody (left) and a (different) patient injected with 47 mg HuMab 5B1 antibody 2 h before injection of 3 mg radiolabeled HuMab 5B (right). C, Fused PET/CT, PET, and contrast-enhanced CT of PDAC liver metastases in a patient who received 47 mg of HuMab 5B1 before injection of the radiolabeled antibody. Small liver metastases measuring less than 5 mm (red arrows) are visualized with high contrast. SUVs values were 101.4, 70.7, and 53.4 g/ml, respectively. Arrowhead indicates splenic infarct.

Article Snippet: The fully human HuMab-5B1 antibody was manufactured for MabVax Therapeutics Holdings, Inc. (San Diego, CA) by Patheon Biologics (Groningen, Netherlands) under current good manufacturing practice (cGMP) guidelines and supplied in sterile vials to MSK.

Techniques: Radioactivity, Standard Deviation, Injection, Positron Emission Tomography-Computed Tomography